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AOD-9604 – 10mg

10mg

AOD-9604 is an artificial fragment of growth hormone C -terminal peptide. It is composed of 177-191 amino acids and has an additional tyrosine in the N-terminus.

$109.99

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What is AOD-9604?

AOD-9604 is an artificial fragment of growth hormone C -terminal peptide. It is composed of 177-191 amino acids and has an additional tyrosine in the N-terminus. Researchers apply it in studies of fat-metabolism in controlled research models in laboratories. The peptide maintains lipolysis without interfering with more general effects of growth-hormone like the stimulation of IGF-1. This narrowed behavior enables researchers to study lipid degradation and fat-store management devoid of extensive hormonal impacts. The compound is provided in the form of a lyophilized powder, which is stable and can be properly prepared to conduct an experiment. Its framework does not degrade easily, which can be used with more protracted laboratory procedures. Its preclinical research is conducted regarding its role in metabolism, cartilage signaling, and models of obesity. The research and laboratory are the only two environments in which all the investigations can be restricted.

AOD-9604 Molecular Formula

AOD-9604 is a 16-amino-acid peptide with a disulfide bridge and the molecular formula C₇₈H₁₂₃N₂₃O₂₃S₂, giving it a molecular weight of approximately 1815.1 daltons. The sulfur atoms form a cyclic bond that enhances stability in laboratory conditions, and researchers rely on this defined composition for consistent results in fat metabolism studies.”

What is AOD-9604 10 MG?

The 10mg vial has a maximum standard of high-purity lyophilized powder which can be used in laboratory research. It is appropriate where extensive experiments or studies that involve high amounts are involved over a long period of time. It is applicable to massive testing by researchers in cell cultures or animal models of fat metabolism and lipolytic pathways. The augmented supply lowers the necessity of re-ordering and facilitates multi-phase and thorough research. The 10 mg vial contains a high-purity, freeze-dried powder suitable for large-scale laboratory studies. This quantity supports multi-phase experiments or high-volume testing in cell cultures or animal models. The sealed, sterile vial can be reconstituted with bacteriostatic water to produce a clear solution for in vitro or preclinical use.

Structural Profile of AOD-9604

AOD-9604 is a 16-amino-acid peptide derived from the C-terminal fragment of growth hormone (residues 177–191) with an added tyrosine at the N-terminus. It has the following order: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe. The two cysteine residues are linked by a disulfide bond, a cyclic type of structure which enhances the stability of the protein when it is being manipulated. Such a design resembles the lipolytic area of growth hormone but it does not have the broader growth-promoting effects. Its small size is more resistant to enzymatic decomposition compared to linear fragments and allows it to be used in the experiment over a long period. These characteristics are useful in accurate study of fat metabolism in preclinical study models.

Laboratory Research on AOD-9604

AOD-9604 is primarily studied in preclinical models by laboratories to investigate the fat-metabolism pathways. A peptide in obese rat models and mice enhances lipolysis by decomposing stored fat to produce free fatty acids. It also suppresses lipogenesis, inhibiting the formation of new fats without stimulating the action of growth-hormone, such as the increase of IGF-1. Experiments using cell-culture reveal that beta-3 adrenergic receptors are stimulated on fat cells, thereby increasing the oxidation of fat. Other studies examine the support of cartilage, in which rabbit and mouse osteoarthritis models reveal maintenance of joint matrix and lower levels of degradation indicators. All studies are still preclinical and concentrate on the selective fat-targeting mechanisms and their comparison with the native growth-hormone fragments. The results inform additional in vitro or animal research designs.

Peptide Interaction in Laboratory Studies

The interactions with adipose cells in laboratory experiments show that AOD-9604 can form an interaction with the adipose cells to induce fat breakdown but not trigger the full growth-hormone receptor pathway. In cell cultures, the peptide stimulates the hydrolysis of triglycerides stored in cells to free fatty acids and glycerol and inhibits lipogenesis by blocking the activity of acetyl CoA carboxylase in cultured adipocytes. However, it does not bind with any importance to GH receptors, or increase IGF-1 levels in test systems, as full growth hormone does. Isolated fat tissue and cell studies demonstrate beta -oxidation pathways activation and beta -3 adrenergic signaling. These interactions allow researchers to study selective lipid metabolism and energy regulation in controlled preclinical experiments.

Production Methodology & Quality Controls

AOD-9604 is a synthetic drug that is synthesized in a solid-phase through peptide synthesis in laboratory settings. The peptide chain is built up stepwise with a solid resin by using the protected amino acids and cleaved, cyclized to create the disulfide bond and purified in a series of steps. The quality of each batch is checked, with HPLC to ensure purity more than 98.Node and mass-spectrometry to establish the molecular identity. Further tests are used to control proper peptide composition and absence of solvents or other toxic substances. These processes are able to be consistent with batch-to-batch as well as offer a research grade peptide, which can be used to perform a reliable laboratory study.

Synthesis & Batch Standards

The synthesis of AOD-9604 involves peptide synthesis in the solid phase in the laboratory. Amino acids are sequentially added in a resin, cleavage, controlled oxidation to create the disulfide bond, and complete purification takes place. Goods that come in batches are subjected to quality tests including HPLC to ascertain purity of over 98 weight and mass spectrometry to determine molecular structure and mass. Further tests are meant to check the right peptide content and no contaminants like endotoxins or solvents left. Such standards ensure research grade and consistent batches that can be used in dependable laboratory research.

Storing AOD-9604

Store lyophilized AOD-9604 vials at -20°C for long-term stability. Keep them protected from light and moisture using the original packaging or opaque containers. Short-term storage at room temperature is acceptable for a few weeks without significant loss of quality. After reconstitution with bacteriostatic water or a suitable solvent, keep the solution at 2–8°C and use it within a limited timeframe. Avoid repeated freeze-thaw cycles, as they can reduce stability. Proper storage ensures consistent results in laboratory experiments.

Intended Research Use & Disclaimer

AOD-9604 is provided solely for laboratory and scientific research. It is supplied as a research chemical and is not approved for human or veterinary use, diagnostic procedures, or therapeutic purposes. No claims regarding safety or effectiveness in living subjects have been evaluated by the FDA or any other regulatory agency. Researchers must follow standard laboratory safety protocols and relevant regulations. Only trained personnel should handle this compound. The supplier is not responsible for misuse, improper storage, or applications outside of controlled research settings. All sales are final, and the buyer assumes full responsibility for compliance and safe laboratory practices.

Referenced Studies

Research Use Only

This product is intended for laboratory research use only. It is not intended for human or animal consumption, or for use in diagnostic or therapeutic procedures.

Chemical Properties

Molecular Formula	C78H123N23O23S2
Molecular Mass	1815.1 g/mol
Monoisotopic Mass	1813.86035961 Da
Polar Area	815 Å²
Complexity	3710
XLogP	-4.8
Heavy Atom Count	126
Hydrogen Bond Donor Count	28
Hydrogen Bond Acceptor Count	28
Rotatable Bond Count	45
CID	71300630
InChI	InChI=1S/C78H123N23O23S2/c1-9-41(8)62(101-68(115)47(18-14-28-86-78(83)84)91-69(116)50(29-38(2)3)95-63(110)45(79)30-43-19-21-44(104)22-20-43)75(122)100-61(40(6)7)74(121)94-49(23-25-56(80)105)67(114)98-55-37-126-125-36-54(65(112)88-32-57(106)89-51(76(123)124)31-42-15-11-10-12-16-42)97-70(117)52(34-102)90-58(107)33-87-64(111)48(24-26-59(108)109)93-73(120)60(39(4)5)99-71(118)53(35-103)96-66(113)46(92-72(55)119)17-13-27-85-77(81)82/h10-12,15-16,19-22,38-41,45-55,60-62,102-104H,9,13-14,17-18,23-37,79H2,1-8H3,(H2,80,105)(H,87,111)(H,88,112)(H,89,106)(H,90,107)(H,91,116)(H,92,119)(H,93,120)(H,94,121)(H,95,110)(H,96,113)(H,97,117)(H,98,114)(H,99,118)(H,100,122)(H,101,115)(H,108,109)(H,123,124)(H4,81,82,85)(H4,83,84,86)/t41-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,60-,61-,62-/m0/s1
InChIKey	GVIYUKXRXPXMQM-BPXGDYAESA-N
IUPAC Name	(2S)-2-[[2-[[(4R,7S,13S,16S,19S,22S,25R)-25-[[(2S)-5-amino-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-22-(3-carbamimidamidopropyl)-13-(2-carboxyethyl)-7,19-bis(hydroxymethyl)-6,9,12,15,18,21,24-heptaoxo-16-propan-2-yl-1,2-dithia-5,8,11,14,17,20,23-heptazacyclohexacosane-4-carbonyl]amino]acetyl]amino]-3-phenylpropanoic acid
Smiles	CC[C@H](C)[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CCCNC(=N)N)CO)C(C)C)CCC(=O)O)CO)C(=O)NCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N

Certificate of Analysis

Quality

Every batch of AOD-9604 – 10mg is tested for purity and identity using industry-standard methods.

HPLC Analysis

High-Performance Liquid Chromatography confirms purity ≥98%. Each batch is analyzed to ensure consistent quality.

Mass Spectrometry (MS)

Identity verification via mass spectrometry confirms correct molecular weight of 4113.58 g/mol.

Third-Party Testing

All products undergo independent third-party laboratory testing for quality assurance.

Request COA

Certificate of Analysis documents are available for all products. Contact us with your order number to request batch-specific documentation.

COA Lab Tests

Each product batch is tested by independent laboratories to verify purity, identity, and quality. The Certificate of Analysis (COA) provides transparent lab results, ensuring the product meets strict research-grade standards.